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Kev sib raug zoo ntawm resveratrol thiab tib neeg kev noj qab haus huv

Xov xwm

Kev sib raug zoo ntawm resveratrol thiab tib neeg kev noj qab haus huv

2024-07-24 11:56:08 dr hab

Resveratrol, uas tsis yog-flavonoid polyphenol organic compound, yog cov tshuaj tua kab mob uas tsim los ntawm ntau cov nroj tsuag thaum txhawb nqa, nrog rau cov tshuaj formula C14H12O3. Nws tuaj yeem ua ke rau hauv cov nplooj txiv hmab txiv ntoo thiab cov tawv nqaij ntawm cov txiv hmab txiv ntoo thiab yog cov khoom siv bioactive hauv cov kua txiv hmab txiv ntoo thiab cov kua txiv hmab txiv ntoo.Resveratrolthiab nws cov derivatives feem ntau pom muaj tsawg kawg yog 72 hom nroj tsuag hauv 31 genera thiab 21 tsev neeg xws li Vitis, Polygonum, txiv laum huab xeeb thiab veratrol, suav nrog cov nroj tsuag tshuaj xws li knotcane, cassia thiab mulberry, nrog rau cov qoob loo xws li txiv hmab txiv ntoo thiab txiv laum huab xeeb. . Lub ntsiab ntuj qhov chaw ntawmresveratrolyog knotweed thiab grapes.ResveratrolNws yooj yim nqus los ntawm qhov ncauj thiab tawm hauv cov zis thiab quav tom qab cov metabolism. Hauv vitro thiab tsiaj sim tau pom tiasresveratrolmuaj antioxidant, anti-inflammatory, anticancer thiab cardiovascular tiv thaiv. Tshawb nrhiav kev sib raug zoo ntawmresveratrolthiab tib neeg kev noj qab haus huv yog qhov tsim nyog rau kev txhawb nqa kev sib sib zog nqus thiab kev siv ntawmresveratrolthiab txhim kho tib neeg kev noj qab haus huv.
2 epx

TEEB MEEM

Kev sim tau pom tias ua ntej kev cuam tshuam nrogresveratroltuaj yeem tiv thaiv iris-induced daim siab raug mob. Tib lub sijhawm,resveratroltau pom tias inhibit daim siab mob thaum lub sij hawm HIRI los ntawm kev cuam tshuam neutrophils. Lub mechanism uasresveratrolregulates neutrophils yog inhibit neutrophils ciaj sia, cell voj voog, migration chemotaxis, oxidative stress, cytokine secretion thiab endothelin-1 autocrine los ntawm inhibiting ERK signaling pathway. Cov ntaub ntawv no muab pov thawj ntau ntxiv rau cov teebmeem immunomodulatory ntawmresveratrolthiab txhawb peb txoj kev nkag siab txog cov tswv yim tiv thaiv kab mob los txhim kho HIRI.
p028 ua

Siv:
WANG YN, Sun XJ, HAN XT, et al.Resveratroltxhim kho hepatic ischemia-reperfusion raug mob los ntawm inhibiting neutrophils ntawm ERK signaling pathway [J]. Biomedicine & Pharmacotherapy, 2023, 160: 114358. DOI: 10.1016/j.biopha.2023.114358.

Raws li kev tshawb fawb preclinical,resveratrolexerts chemoprotective thiab chemosensitizing los ntawm anti-plasticity, antioxidant, anti-inflammatory, thiab pro-apoptotic hom kev ua. Ntxiv nrog rau nws cov teebmeem anticancer,resveratrolkuj ua raws li tus neeg nruab nrab ntawm kev siv tshuaj khomob-vim cov tshuaj toxicity hauv cov hlwb / cov nqaij mos. Raws li cov tshuaj tiv thaiv qog nqaij hlav (tshaj tawm ntau lub tswv yim), cov tshuaj sib xyaw ua ke txhim kho nws cov txiaj ntsig kho mob los ntawm superposition thiab kev sib koom ua ke, thiab txo cov kev cuam tshuam ntawm kev siv tshuaj tua kab mob.

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Hauv cov ntsiab lus, tsab xov xwm no tshuaj xyuas cov tshuaj rhiab heev ntawmresveratrolntawm cov qog hlwb rau cov tshuaj siv tshuaj khomob los ntawm kev xav ntawm cell plasticity, uas yog qhov tseem ceeb heev rau kev hloov pauv ntawm cov hlwb mus rau TME thaum lub sijhawm hloov qog cell thiab metastasis. Qhov no tseem muab kev txhawb zog tshiab rau kev tshawb fawb ntxiv ntawm cov qog nqaij hlav qog noj ntshav thiab resveratrol-mediated plasticity inhibition, qhia tau hais tiasresveratrol, ua ib qho phytochemical nquag, yuav ua lub luag haujlwm hauv kev tiv thaiv thiab kho CRC yav tom ntej. lub luag haujlwm tseem ceeb.

Yog xav paub ntxivcov ntaub ntawvtxog peb cov khoom thiab cov kev pabcuam thov hu rau peb.

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Resveratrol:
https://www.xahealthway.com/polygonum-cuspidatum-extract-trans-resveratrol-98-hplc-product/