A magical herb given by God - Gastrodia elata——Part Two

二、The multiple functions of Gastrodia elata

Gastrodia elata contains a variety of active ingredients such as phenolic substances (such as gastrodin), gastrodia polysaccharides, organic acids, vitamin A, etc. These ingredients have the functions of protecting nerves, calming and hypnotizing, improving learning and memory, anti-depression, lowering blood pressure, promoting angiogenesis, and protecting cardiomyocytes.

Protects the Nervous System:

A number of in vivo and in vitro studies have shown that gastrodin has an improving effect on central nervous system diseases such as epilepsy, Alzheimer's disease, and Parkinson's disease. Gastrodin can significantly increase cell viability, reduce the release of lactate dehydrogenase (LDH), and has a protective effect on damaged neurons. Gastrodin inhibits the decrease in catalase (CAT), glutathione (GSH), superoxide dismutase (SOD), glutathione reductase (GR) and total antioxidant (T-AOC) levels , and inhibit the increase in malondialdehyde (MDA) levels, thereby achieving neuroprotective and antioxidant effects.

In addition, the active compounds of Gastrodia elata (gastrodin, 4-hydroxybenzyl alcohol, vanillin, etc.) show strong improvement effects on depression models. The potential mechanisms include neurotransmitters, antioxidants, anti-inflammatory, and regulation of hypothalamus- Pituitary-adrenal axis, neurotrophic effects, regulatory stem cells, enhanced neuroplasticity and neuroprotection.

Hypnosis and sedation：

Gastrodia elata has a hypnotic and sedative effect. Studies have shown that the effect of fresh Gastrodia elata on sleep is mainly due to phenolic substances, and the effect of gastrodin among phenolic substances is particularly prominent. The hypnotic and sedative mechanism of Gastrodia elata may be related to regulating the activity of the central dopamine system and regulating monoamine neurotransmitters in the hypothalamus and hippocampus.

Protecting myocardial cells: Studies have shown that the protective effect of Gastrodia elata on myocardial cells is mainly related to gastrodin. Gastrodin can inhibit the opening of the mitochondrial permeability transition pore (mPTP) during oxidative stress damage of myocardial cells, thereby reducing cell apoptosis and alleviating oxidative stress damage. Gastrodin can upregulate the expression of 14-3-3η protein, inhibit oxidative damage of myocardial cells, downregulate the degree of oxidative stress of myocardial cells, reduce cell apoptosis, and have anti-inflammatory effects.

Liver protection:

Gastrodin can prevent the loss of mitochondrial membrane potential of hepatocytes caused by alcohol, reduce the release of mitochondrial cytochrome C, inhibit the activation of caspase-3 in hepatocytes, thereby inhibiting hepatocyte apoptosis, restoring abnormal liver function to normal, and effectively improving pathological changes in the liver.
Boost the immune system:

Gastrodia polysaccharide can promote the increase of immunoglobulin levels in mice, improve the thymus index and spleen index. In addition, Gastrodia injection can improve the phagocytic function and serum lysozyme activity of mice, enhance the immune response and non-specific effects of mouse T cells, and promote the formation of specific antibodies.

三、Gastrodia elata products
Healthway has a health food product that is 100% pure Gastrodia elata powder that can be taken with water, milk, yogurt, and can also be used in baking.

For more information about our products and services please contact us.

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