Senolytics (senescent cell lysing agents) imhando yemishonga inorwisa kuchembera inogona kubvisa maseru maseru. Iyo inonyanya kuzivikanwa inosanganisira rapamycin, quercetin yakasanganiswa nedasatinib, nezvimwe.
Imwe nyaya muna 1966 yakaratidza izvozvo
fisetinyakanga iri imwe yeflavonoids ine simba rinorwisa mabhakitiriya raizivikanwa panguva iyoyo. Inogona kuvharidzira zvinobudirira kukura kwebhakitiriya seStaphylococcus aureus. Muna 2021, Yunivhesiti yeMinnesota neMayo Clinic vakabatana vakaburitsa ongororo inoratidza kuti senolytics yakaderedza zvakanyanya kufa kwemakonzo echikuru akatapukirwa nebeta-coronavirus. Mushonga unorwisa kuchembera uyu unonzi fisetin.
01 Chii chinonzi fisetin?
Fisetin, anozivikanwawo se
fisetin, imhando yemhando yemhando ye flavonoid yakagadzirwa kubva mumiti yakadai seAnacardiaceae. Fisetin inowanikwawo mumichero nemiriwo uye ine antioxidant, anti-inflammatory uye mamwe pharmacological properties.
02 Chii chinonzi fisetin?
Fisetin inonzi bioflavonoid antioxidant iyo inogona kubatsira kuchengetedza mazinga e glutathione uye mitochondrial basa mukuvapo kwekunetseka kweoxidative. Iine mukana wekuyambuka ropa-brain barriers, iyo inogona kubatsira kuchengetedza neuronal basa.
01.Fisetininogona kuchenesa mahara radicals uye kuwedzera glutathione
Fisetin inobvisa zvakananga radicals emahara, inosimudzira mazinga eglutathione, uye inogona kubatsira kudzora kugadzirwa kwemapuroteni mazhinji anobatanidzwa mukudzivirira muviri kubva kuoxidative kusagadzikana uye kuchengetedza redox homeostasis. Iyi ndiyo nzira iyo glutathione inowana iyo antioxidant mhedzisiro.
02.Fisetin inewo anti-tumor madhara.
Kuedza kwechiito kwakaratidza kuti ine anti-human cancer cancer maseru, anti-uterine cancer maseru, anti-munhu cancer cancer maseru uye anti-human colon cancer maseru. Maitiro ayo makuru ndeyekukurudzira kusiyanisa kwenhengo yekenza maseru kuita akajairwa maseru nekushandura kenza cell genes.
03.Fisetin inewo zvakasiyana-siyana zvinokonzerwa nehutano hwehuropi, cognition uye chiyeuchidzo.
Zvakawanda zvekutsvakurudza pamusoro peizvi zvakaitwa paSalk Institute yeBiological Studies muSan Diego, inotarisa kushandiswa kwayo se "nootropic substance" uye "neurotrophic factor." Sezvambotaurwa, inogona kuyambuka chipingamupinyi cheropa-uropi uye yobva yaita "kuchekerera" mhedzisiro, ichibvisa maseru maseru uye ichibvumira masero ane hutano kutsiva ekare, asina basa uye anogona kukuvadza maseru. Uye, vamwe vanhu vanotenda kuti kugona kwayo kunokonzerwa nequercetin. Kaviri kupfuura yekutanga.
03 Pfupisa
Fisetin musanganiswa wechisikigo wakatorwa kubva muzvirimwa zvine mabhenefiti akawanda uye inhengo yeboka renolytics nebasa rayo mukubvisa maseru. Kune dzakawanda
fisetinzvigadzirwa pamusika zvino. Kana uine pfungwa dzekurwisa kuchembera, ndinotenda fisetin isarudzo yakanaka.
For moreruzivonezvezvigadzirwa zvedu nemasevhisi ndapota taura nesu.
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Irene@xahealthway.com
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