I-Senolytics (i-senescent cell lysing agents) luhlobo lweziyobisi ezichasayo ezinokuphelisa iiseli zesenescent. Ezona ziyaziwa kakhulu ziquka i-rapamycin, i-quercetin idibene ne-dasatinib, njl.
Inqaku lowe-1966 labonisa oko
i-fisetinyayiyenye yeeflavonoids ezinempembelelo enamandla yokulwa neebhaktiriya ezaziwa ngelo xesha. Inokuthintela ngokufanelekileyo ukukhula kweebhaktheriya ezifana ne-Staphylococcus aureus. Ngo-2021, iYunivesithi yaseMinnesota kunye neKliniki yaseMayo ngokudibeneyo bakhuphe uphononongo olubonisa ukuba iisenolytics zalehlisa kakhulu izinga lokusweleka kweempuku ezisele zikhulile ezosulelwe yi-beta-coronavirus. Eli chiza lichasene nokuguga yifisetin.
01 Yintoni i-fisetin?
Fisetin, eyaziwa ngokuba
i-fisetin, luhlobo lwendalo ye-flavonoid ekhutshwe kwizityalo ezifana ne-Anacardiaceae. I-Fisetin ifumaneka kwiziqhamo kunye nemifuno kwaye ine-antioxidant, i-anti-inflammatory kunye nezinye iimpawu ze-pharmacological.
02 Yintoni umsebenzi wefisetin?
I-Fisetin i-antioxidant ye-bioflavonoid enokunceda ukugcina amanqanaba e-glutathione kunye nomsebenzi we-mitochondrial phambi koxinzelelo lwe-oxidative. Inamandla okuwela umqobo wegazi-ingqondo, enokunceda ukugcina umsebenzi we-neuronal.
01.Fisetininokukhupha iiradicals zasimahla kwaye yandise iglutathione
I-Fisetin ikhupha ngokuthe ngqo i-radicals yamahhala, iphakamisa amanqanaba e-glutathione, kwaye inokunceda ukulawula ukuveliswa kweeprotheni ezininzi ezibandakanyekayo ekukhuseleni umzimba kuxinzelelo lwe-oxidative kunye nokugcina i-redox homeostasis. Le yindlela apho i-glutathione ifezekisa iziphumo zayo ze-antioxidant.
I-02.Fisetin nayo ineempembelelo ezichasene ne-tumor.
Uvavanyo lomsebenzi lubonakalise ukuba inomhlaza wemiphunga echasene nomntu, iiseli ezichasene nesibeleko somhlaza, iiseli ezichasene nomhlaza wolusu lomntu kunye neeseli ezichasene nomhlaza wekoloni. Eyona ndlela iphambili kukukhuthaza ukwahlulwa kwelungu leeseli zomhlaza kwiiseli eziqhelekileyo ngokuguqula imizila yeeseli zomhlaza.
I-03.Fisetin nayo ineempembelelo ezizodwa kwimpilo yengqondo, ukuqonda kunye nememori.
Uninzi lophando kule nto luqhutywe kwi-Salk Institute eyaziwayo ye-Biological Studies e-San Diego, igxininise ekusebenziseni kwayo "njengento ye-nootropic" kunye ne "neurotrophic factor." Njengoko bekutshiwo ngaphambili, inokuwela umqobo wegazi-ingqondo kwaye isebenzise isiphumo "sokuthena", icoca iiseli zesenescent kwaye ivumele iiseli ezisempilweni ukuba zithathe indawo yeeseli ezindala, ezingenamsebenzi kunye nezinokuba yingozi. Kwaye, abanye abantu bakholelwa ukuba amandla ayo ngenxa ye-quercetin. Ngokuphindwe kabini njengenkulumbuso.
03 Shwankathela
I-Fisetin yimbumba yendalo ekhutshwe kwizityalo ezineenzuzo ezininzi kwaye ilungu leqela le-senolytics ngendima yalo yokucoca iiseli ze-senescent. Zininzi
i-fisetiniimveliso kwimarike ngoku. Ukuba unemibono echasene nokuguga, ndiyakholelwa ukuba i-fisetin yinto efanelekileyo yokukhetha.
Ngokungakumbiulwazimalunga neemveliso kunye neenkonzo zethu nceda uqhagamshelane nathi.
Imfonomfono: 86 18691558819
Irene@xahealthway.com
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