I-Senolytics (i-senescent cell lysing agents) iwuhlobo lwezidakamizwa ezilwa nokuguga ezingaqeda amangqamuzana ezinzwa. Ezaziwa kakhulu zihlanganisa i-rapamycin, i-quercetin ehlanganiswe ne-dasatinib, njll.
Isihloko sango-1966 sabonisa lokho
i-fisetinkwakungenye ye-flavonoid enomphumela onamandla we-antibacterial owaziwa ngaleso sikhathi. Ingakwazi ukuvimbela ngempumelelo ukukhula kwamagciwane afana ne-Staphylococcus aureus. Ngo-2021, iNyuvesi yaseMinnesota kanye neMayo Clinic ngokuhlanganyela bakhipha ucwaningo olukhombisa ukuthi ama-senolytics anciphisa kakhulu izinga lokufa kwamagundane asebekhulile angenwe yi-beta-coronavirus. Lesi sidakamizwa sokulwa nokuguga yi-fisetin.
01 Yini i-fisetin?
I-Fisetin, eyaziwa nangokuthi
i-fisetin, wuhlobo lwenhlanganisela ye-flavonoid yemvelo ekhishwe ezitshalweni ezifana ne-Anacardiaceae. I-Fisetin itholakala nasezithelo nasemifino futhi ine-antioxidant, anti-inflammatory kanye nezinye izakhiwo zemithi.
02 Yini umsebenzi we-fisetin?
I-Fisetin iyi-antioxidant ye-bioflavonoid engasiza ekugcineni amazinga e-glutathione kanye nomsebenzi we-mitochondrial lapho kukhona ukucindezeleka okwenziwe nge-oxidative. Inamandla okuwela umgoqo wegazi-wobuchopho, ongasiza ekugcineni ukusebenza kwe-neuronal.
01.I-Fisetiningasusa ama-radicals mahhala futhi ithuthukise i-glutathione
I-Fisetin isusa ngokuqondile ama-radicals mahhala, ithuthukise amazinga e-glutathione, futhi ingasiza ekulawuleni ukukhiqizwa kwamaprotheni amaningi ahilelekile ekuvikeleni umzimba ekucindezelekeni kwe-oxidative nokugcina i-redox homeostasis. Lena indlela i-glutathione efinyelela ngayo imiphumela yayo ye-antioxidant.
I-02.I-Fisetin nayo inemiphumela yokulwa ne-tumor.
Ukuhlolwa komsebenzi kufakazele ukuthi inamaseli omdlavuza wamaphaphu alwa nomuntu, amaseli omdlavuza wesibeletho, amangqamuzana omdlavuza wesikhumba omelene nomuntu kanye namaseli omdlavuza wamaphaphu alwa nomdlavuza. Indlela yayo eyinhloko ukunxenxa ukuhlukaniswa kwesitho samaseli omdlavuza abe amaseli ajwayelekile ngokuguqula izakhi zofuzo zamangqamuzana omdlavuza.
I-03.Fisetin nayo inemiphumela eyingqayizivele empilweni yobuchopho, ukuqonda kanye nenkumbulo.
Ucwaningo oluningi ngalokhu lwenziwe esikhungweni esidumile i-Salk Institute for Biological Studies e-San Diego, sigxile ekusetshenzisweni kwayo "njengento ye-nootropic" kanye "ne-neurotrophic factor." Njengoba kushiwo ngaphambili, ingawela umgoqo wobuchopho begazi bese yenza umphumela "wokuthena", ikhiphe amangqamuzana abomvu egazi futhi ivumele amaseli anempilo ukuthi athathe indawo yamaseli amadala, angenamsebenzi futhi okungenzeka ukuthi ayingozi. Futhi, abanye abantu bakholelwa ukuthi ikhono layo libangelwa i-quercetin. Okuphindwe kabili kunakuqala.
03 Fingqa
I-Fisetin iyinhlanganisela yemvelo ekhishwe ezitshalweni ezinezinzuzo eziningi futhi iyilungu leqembu le-senolytics ngendima yayo ekuhlanzeni amaseli e-senescent. Kuningi
i-fisetinimikhiqizo emakethe manje. Uma unemibono elwa nokuguga, ngikholwa ukuthi i-fisetin iyisinqumo esihle.
Ukuze uthole okwengeziweulwazimayelana nemikhiqizo namasevisi ethu sicela usithinte.
Umakhalekhukhwini: 86 18691558819
Irene@xahealthway.com
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