13 effects and side effects of Spirulina (blue algae) (please be careful with the 7 contraindications) Part TWO

8． Spirulina Benefits Chronic Hepatitis C

Hepatitis C virus accounts for about 15% to 20% of acute hepatitis cases. After acute infection, about 50% to 80% of hepatitis C patients will develop chronic infection.
People with chronic hepatitis C are at high risk for life-threatening complications, including cirrhosis in 20 percent and hepatocellular carcinoma in 4 to 5 percent per year.
Epidemiological studies have also shown that hepatitis C is associated with many extrahepatic manifestations, including insulin resistance, type 2 diabetes, glomerular disease, oral manifestations, etc.
A randomized, double-blind, comparative study of 66 patients with chronic hepatitis C virus infection over a period of 6 months showed that compared with silymarin, spirulina helped improve viral load, liver function, and health-related life outcomes. quality and sexual function. Note 6
*Conclusion: Spirulina may have a positive effect on chronic hepatitis C

9. Spirulina Benefits Thalassemia
Thalassemias are a group of inherited blood disorders characterized by abnormalities in hemoglobin synthesis and come in three main forms: severe, intermediate and mild.
Patients with thalassemia major usually develop severe anemia within two years of birth and require regular blood transfusions.
Routine transfusion therapy may result in complications related to iron overload, including developmental delay and failure or delay in sexual maturation. Serious conditions may cause abnormalities in the heart (dilated cardiomyopathy or rare arrhythmias), liver (fibrosis and cirrhosis), and endocrine glands (diabetes, hypogonadism, and parathyroid, thyroid, and pituitary insufficiency).
An interventional study (3 months, 60 children with thalassemia major) pointed out that taking spirulina can help improve hemoglobin levels and left ventricular global longitudinal strain (Left ventricular global longitudinal strain), and reduce the number of blood transfusions.
*Conclusion: For subjects with thalassemia major, spirulina supplementation may be beneficial in reducing the frequency of blood transfusions and preventing heart damage, but it is limited by the small sample size and more research is needed to further verify it.

11. Spirulina Benefits Non-Alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease is the most common chronic liver disease, with a natural history that includes non-alcoholic steatohepatitis and cirrhosis, and will become the leading cause of liver transplantation by 2030
The spread of sedentary lifestyles and poor eating habits is the main reason for the increase in prevalence. The prevalence of the disease in type 2 diabetes patients is 50% to 75%, and it is as high as 80% to 90% in obese patients.
In addition, patients are at high risk for cardiovascular diseases (left ventricular dysfunction, atherosclerotic cardiovascular disease, cardiac conduction system abnormalities, and ischemic stroke), which are the leading causes of death.
An interventional study (6 months, 14 patients with non-alcoholic fatty liver disease) pointed out that oral spirulina can help reduce aspartate aminotransferase (AST), alanine aminotransferase (ALT), γ- Glutaminyl transpeptidase (GGT), low-density lipoprotein cholesterol, total cholesterol, ratio of total cholesterol to high-density lipoprotein cholesterol, insulin resistance, and body weight indicators. Note 8
In addition, quality of life, average levels of HDL cholesterol and hemoglobin were significantly increased
＊Conclusion: For non-alcoholic fatty liver disease, spirulina may be able to bring positive help, but it is limited by the small sample size and more research is needed to further verify it.

11. Spirulina improves nutritional status

Nutritional status is an important factor in maintaining health in older adults and is an important determinant of the aging process. Nutritional deficiencies often occur in the elderly and indirectly lead to physical decline, such as: impaired muscle function, bone loss, immune dysfunction, anemia , cognitive decline, poor wound healing, delayed recovery from surgery, and increased mortality.
In addition, malnutrition is the main factor causing stunted growth and death among children under 5 years old around the world, especially in developing countries. It is estimated that about 140 million children are malnourished.
A prospective study (prospective study, lasting 30 days, with 50 malnourished African children) pointed out that spirulina can significantly improve the nutritional status of the subjects (including hemoglobin, anemia, total protein and other indicators).
Spirulina has been eaten by humans. According to the Bible, it can be traced back to the Egyptian era thousands of years ago. If it is in a pollution-free state, it can be regarded as a very safe natural food.

Adverse reactions or minor side effects that have been reported include nausea, vomiting, diarrhea, abdominal discomfort, fatigue, headache, dizziness, edema, muscle pain, facial flushing, and sweating.

Since Spirulina is easily affected by the environment when growing, if the culture water is polluted, it may produce products full of bacteria and harmful substances (microcystins, toxic metals and harmful bacteria). If not eaten, it may cause liver damage and stomach pain. , nausea, vomiting, weakness, thirst, rapid heartbeat, shock and death, etc. Therefore, when purchasing, please look for reputable brands that have been inspected by third-party manufacturers.

Safety precautions (7 taboos)
1. Do not use it if you are preparing for pregnancy, pregnant women, or lactating women (because the related safety is unknown)
2. Do not use it if you are allergic to iodine or have hyperthyroidism (because spirulina contains iodine)
3. Do not use if you are allergic to seafood or seaweed
4. Patients with autoimmune diseases, such as multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, etc., please avoid use (because spirulina will activate immune cells and may aggravate the condition)
5. Do not use it for patients with phenylketonuria (because spirulina contains phenylalanine, which may worsen phenylketonuria)
6. Do not use this product if you have abnormal coagulation function or are taking anticoagulants. Because Spirulina has an anticoagulant effect, it may increase the patient’s risk of bruising and bleeding.
7. Do not use it together with drugs that have immunosuppressive effects. It may affect the efficacy of the drug. Common drug names are: (azathioprine), basiliximab), (cyclosporine), (daclizumab), ( Moromumab), (Mycophenolate mofetil), (Tacrolimus), (Rapamycin), (Prednisone), (Corticosteroids)

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